Induction of pancreatic differentiation by signals from blood vessels

In this publication, the Melton group is one of the first to discover the role of Angiocrine functions in pancreatic differentiation. Evidence for the importance of vessel-derived growth factors was found in both xenopus and mouse models.

Science. 2001 Oct 19;294(5542):564-7. Epub 2001 Sep 27.

Lammert E1, Cleaver O, Melton D.

1Department of Molecular and Cellular Biology, Howard Hughes Medical Institute, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA.