Our values are the critical foundation upon which we have built Angiocrine Bioscience.

Esprit de Corps • Commitment • Excellence • Laser Focus

Our team challenges conventional wisdom and pushes the boundaries of scientific discovery and innovation. Our values are reflected in how we think about the patients we aspire to help, the science we do, how we operate as a company, and who we hire.

We look for energetic, creative, self-motivated people who enjoy the breadth and depth of activities one finds in a small, entrepreneurial company. In joining Angiocrine Bioscience, employees are part of a vibrant multi-disciplinary team, committed to developing innovative engineered cellular therapies for treating numerous medical conditions.

Angiocrine Bioscience is committed to the principles of equal employment opportunity. Applicants are considered for all positions without regard to race, sex, sexual orientation, color, religion, national origin, age and disability or any other status protected by applicable law.

Current Openings
Quality Control Supervisor

The Quality Control Supervisor will be part of the Angiocrine QC team that supports all QC laboratory activities in support of release testing of a cell-based therapy undergoing clinical investigation. A successful candidate should have some experience in cell/gene-therapy product testing under GMP, including familiarity with aseptic technique, immunoassays, flow cytometry, and PCR. This is a full-time position and will report to the Director of Quality.

Position Responsibilities and Requirements:

  • Working with cells and products of animal or human origin
  • Working with replication-incompetent retrovirus
  • Working with chemicals or potential hazard
  • Knowledge of current good manufacturing practices (cGMP) as they apply to Quality Control
  • Supervise daily activities to maintain QC laboratory in a GMP-compliant state, including
    • Keeping current on required training documents
    • Following standard operating procedures (SOPs), protocols, and other instructions from management
    • Ensuring that equipment/instrument maintenance, calibration, and cleaning is properly documented
    • Ensuring segregation of GMP-related materials and test samples
    • Performing release testing for incoming raw materials
    • Maintaining cleanliness and organization of laboratory environment
  • Oversee GMP bioanalytical release testing for cell banks and/or finished cell-based drug products
  • Oversee GMP stability testing for materials, cell banks, and/or finished drug products
  • Conduct out-of-specification (OOS) investigations and deviations
  • Conduct peer review of data generated in QC lab
  • Oversee inventory of laboratory consumables
  • Oversee the validation of bioanalytical test methods
  • Oversee the qualification of equipment/instruments
  • Oversee data trending and other quality metrics
  • Manage QC personnel against performance objectives

Some weekend work may be required depending on testing schedules.
Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Preferred Education and Experience

  • Related Bachelor’s degree (e.g. biology, biotechnology, biochemistry)
  • 5+ years work-related experience in cGMP QC laboratory setting
  • Working familiarity with software such as Microsoft Word, Excel, and PowerPoint
  • Working experience with adherent cells
  • Bioanalytical skills with hands-on knowledge/experience in immunoassay/ELISA, flow cytometry, PCR, and/or other bio-analytical techniques.
  • Effective and clear written and verbal communication
  • Ability to work in a high paced team environment.

Additional Information:

This position is based in San Diego, CA.

Angiocrine is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Apply Now
Quality Control Associate

The Quality Control Associate will be part of the Angiocrine QC team that supports all QC laboratory activities in support of release testing of a cell-based therapy undergoing clinical investigation. A successful candidate should have some experience in cell/gene-therapy product testing under GMP, including familiarity with aseptic technique, immunoassays, flow cytometry, and PCR. This is a full-time position and will report to the QC Supervisor/Manager.

Position Responsibilities and Requirements:

  • Working with cells and products of animal or human origin
  • Working with replication-incompetent retrovirus
  • Working with chemicals or potential hazard
  • Knowledge of current good manufacturing practices (cGMP) as they apply to Quality Control
  • Execute daily activities to maintain QC laboratory in a GMP-compliant state, including
    • Keeping current on required training documents
    • Following standard operating procedures (SOPs), protocols, and other instructions from management
    • Ensuring that equipment/instrument maintenance, calibration, and cleaning is properly documented
    • Ensuring segregation of GMP-related materials and test samples
    • Performing release testing for incoming raw materials
    • Maintaining cleanliness and organization of laboratory environment
  • Perform GMP bioanalytical release testing for cell banks and/or finished cell-based drug products
  • Perform GMP stability testing for materials, cell banks, and/or finished drug products
  • Participate in out-of-specification (OOS) investigations and deviations
  • Conduct peer review of data generated in QC lab
  • Maintain inventory of laboratory consumables
  • Assist in the validation of bioanalytical test methods
  • Assist in the qualification of equipment/instruments

Some weekend work may be required depending on testing schedules. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Preferred Education and Experience

  • Related Bachelor’s degree (e.g. biology, biotechnology, biochemistry)
  • 1+ years work-related experience in cGMP QC laboratory setting
  • Working familiarity with software such as Microsoft Word, Excel, and PowerPoint
  • Working experience with adherent cells
  • Bioanalytical skills with hands-on knowledge/experience in immunoassay/ELISA, flow cytometry, PCR, and/or other bio-analytical techniques.
  • Effective and clear written and verbal communication
  • Ability to work in a high paced team environment.

Additional Information:
This position is based in San Diego, CA.
Angiocrine is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Apply Now
Laboratory Research Associate

Conduct pre-clinical cell-based experiments.

Position Role & Responsibilities:

  • Conduct pre-clinical cell-based experiments.
  • Works independently on assigned projects.
  • Provide support in experimental design and establishing methods and standard operating procedures.
  • Analyze data and present research findings to the group.
  • Interact and collaborate with other members of the R&D team.
  • Participate in routine lab operations (lab maintenance, safety inspections, etc.), equipment maintenance, restocking and/or other duties.

Position Requirements:

  • Education: Bachelors or Masters degree in cell biology, molecular biology, biochemistry, immunology, or related field; 3 or more years relevant lab experience in academia or equivalent industry experience preferred.
  • Candidates with hands-on experience working with cell culture, basic molecular biology laboratory skills (including qPCR) and immunologic tools such as immunohistochemistry, immunofluorescence, flow cytometry, and/or ELISAs, strongly preferred
  • Candidate must:
    • Have ability to execute experiments with minimal technical supervision within parameters of instructions given, prescribed routines, and standard accepted practices.
    • Have ability to learn and carry out new experimental procedures with accuracy and efficiency.
    • Be able to meet deadlines.
    • Have records maintenance skills.
    • Have skills to perform data analysis and troubleshooting.
    • Be able to work collaboratively with other cross-functional Angiocrine team members.

Additional Desired Skills and Knowledge

  • While not a requirement, applicants with a strong background in microvascular biology and/or tissue regeneration are preferred.
  • Experience with isolation of primary endothelial cells.
  • Effective and clear written and verbal communication.
  • Enjoy a fast-paced environment where evolutionary changes are a constant and where proactive ‘can do’ attitude, sense of urgency and friendly personalities are prized.

Non-standard Work Schedule and work environment Requirements

  • Occasional weekday evenings and/or weekend days

Additional Information:
This position is based in San Diego, CA.
Angiocrine is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Apply Now