Angiocrine functions of organ-specific endothelial cells
Abstract: Endothelial cells that line capillaries are not just passive [...]
Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells
Abstract: Pluripotent stem cells (PSCs) represent an alternative hematopoietic stem [...]
Reprogramming human endothelial cells to haematopoietic cells requires vascular induction
Abstract: Generating engraftable human haematopoietic cells from autologous tissues is [...]
The perivascular niche regulates breast tumor dormancy
The goal of Ghajar and colleauges was to understand the [...]
Endothelium: from cellophane to orchestral maestro
This review article by one of the pioneers in vascular [...]
Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells
Dr. John Chute and colleagues identify pleiotrophin as a regulator [...]
Identification of a clonally expanding haematopoietic compartment in bone marrow
This work provides a detailed structure of the vascular niche [...]
Circulating Tumor Cells from Prostate Cancer Patients Interact with E-Selectin under Physiologic Blood Flow
Gakhar and colleagues investigated the ability for prostate cancer (PCa) [...]
Endothelial and perivascular cells maintain haematopoietic stem cells
Dr. Sean Morrison’s laboratory used a generous supply of transgenic [...]
Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells
Here is laid out in detail the alterations to the [...]