Liver organogenesis promoted by endothelial cells prior to vascular function

Angiocrine factors from the vasculature were required to initiate proper hepatic outgrowth and morphogenesis.

Science. 2001 Oct 19;294(5542):559-63. Epub 2001 Sep 27.

Matsumoto K1, Yoshitomi H, Rossant J, Zaret KS.

1Cell and Developmental Biology Program, Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA.

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