The intricacies of the vascular niche in vivo was elucidated in both steady state and regenerating conditions via the transcriptional profiling of various tissues. This encyclopedic database identified the angiocrine factors, cell surface receptors, and the mechanisms of endothelial cell heterogeneity.
Dev Cell. 2013 Jul 29;26(2):204-19. doi: 10.1016/j.devcel.2013.06.017. Epub 2013 Jul 18.
Nolan DJ1, Ginsberg M, Israely E, Palikuqi B, Poulos MG, James D, Ding BS, Schachterle W, Liu Y, Rosenwaks Z, Butler JM, Xiang J, Rafii A, Shido K, Rabbany SY, Elemento O, Rafii S.
1Department of Genetic Medicine, Howard Hughes Medical Institute, Weill Cornell Medical College, New York, NY 10065, USA.